Archive for the tag: Secondary

Wounds and healing 6, Primary and secondary healing

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Healing by primary intention
A wound will heal by primary intention if the edges of the wound can be approximated together. Some form of wound closure is normally employed to keep the wound edges closed. Common ways of achieving closure and stability of the wound edges include adhesive strips, sutures or super glue.
Advantages of healing by primary intention
Approximation and stabilisation will allow the edges of a wound to heal directly into each other. In primary healing the process is fairly rapid, normally wound edges will be closed with sufficient tensile strength to remove the sutures after 7-10 days. However, it takes much longer than this to restore full strength to the wound, even after 2 weeks the wound only has 20% of full strength. If the edges of a wound are closed, the surface area of the wound is reduced. This means that there will be a minimal amount of scar tissue formed, giving good cosmetic and functional results. As the wound is closed, there is less opportunity for secondary colonisation or infection to enter the wound from outside sources of microbiological contamination.
Potential problems with primary intention
Because the wound edges are closed, there is the possibility that foreign material or bacteria may be enclosed within the wound. This will allow any bacteria present to multiply and lead to wound infection with possible abscess formation. Also the presence of foreign material can lead to future complications such as pain and damage to tissues. If foreign material can be removed before closure, this particular complication may be prevented; this is one reason why wound exploration is so vital. If the wound is likely to be contaminated with bacteria from the implement which made the wound, then again it is unwise to close the wound, unless the practitioner feels they are able to adequately wash away the contamination with irrigation or other wound cleaning procedures. When primary healing is not possible, or is not advisable, healing by secondary intention will be used.

Wound Healing: Mechanism, Types, Primary, Secondary & Tertiary intention of healing & Complications

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Hello students, Welcome back!
Wound healing is an important topic in the subject of general pathology. It is important to understand the concept behind the healing process.
In this video, I discuss about the ways of healing in different tissues, such as Resolution & Repair, and the mechanism of healing in those instances.
The healing process involves 3 main steps.
1. Hemostasis
2. Inflammation
3. Proliferation
In the video, I discuss these steps in great details along with the chemical mediators controlling each step.
I also discuss about the healing of deep skin wounds; Primary, Secondary, & Tertiary intention of healing.
If you have any question or doubt regarding this topic, feel free to post them in the comment section. We would love to hear from you.
If you liked the video, please hit the like button, & subscribe.
Thanks for watching!
See you soon in the next video!
Try out Med Today’s videos on;
Neoplasia :- https://youtu.be/s5CnwS6QVC8
Acute inflammation :- https://youtu.be/HrFb0axflGY
Chronic inflammation :- https://youtu.be/Ie30O6zvEnk
Cell adaptations :- https://youtu.be/AOqn_y2YsuY
Cell injury :- https://youtu.be/-Ph2uhw9BhE
Cell death :- https://youtu.be/P2rAeaR_zuY
Granulomatous inflammation :- https://youtu.be/rVaek7-RO0w
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In This short tutorial i have tried to explain the concepts in understanding the concepts of tissue repair. in this part 1. i have discussed in detail about “regeneration” and its mechanism taking liver as an example.

The earlier videos on inflammation can be accessed here https://www.youtube.com/playlist?list…​

You can learn more about amyloidosis here https://www.youtube.com/playlist?list…​

#ilovepathology​

Click on website http://ilovepathology.com/​ for more content for undergraduate students in pathology.

Please feel free to post queries or comment on the video😊 Good luck.
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